4.6 Article

A Bodipy-based derivative for selective fluorescence sensing of homocysteine and cysteine

Journal

NEW JOURNAL OF CHEMISTRY
Volume 35, Issue 1, Pages 61-64

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0nj00720j

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Funding

  1. National Natural Science Foundation of China [20972170]
  2. State Key Laboratory of Oxo Synthesis & Selective Oxidation [OSSO2008kjk6]
  3. Natural Science Foundation of Gansu province [096RJ2A033]

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A method for the selective fluorescence sensing of homocysteine (Hcy) and cysteine (Cys) under neutral pH conditions, based on the reaction of the simple aldehyde containing Bodipy dye with Hcy/Cys, has been developed. The location of the aldehyde group at the Bodipy core is important and has an effect on the cyclization with Hcy/Cys.

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