Journal
NEW JOURNAL OF CHEMISTRY
Volume 32, Issue 10, Pages 1659-1672Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b803866j
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Funding
- Pfizer
- Astra Zeneca
- Merck
- Syngenta
- EPSRC
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In this feature article we will focus on the issues relating to the crystal growth of co-crystals, with a particular emphasis on drug development. The initial focus of this perspective is on the relevant literature examples that may be able to inform our understanding with regards co-crystal crystallisation and the allied supramolecular concepts. The second part of this perspective contains selected examples from our own work, which add to the literature perspective. Topics include; nucleation templates, in situ synchrotron XRD studies, solid-state synthesis through mixing and screening strategies.
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