4.8 Article

Exanthematous Drug Eruptions

Journal

NEW ENGLAND JOURNAL OF MEDICINE
Volume 366, Issue 26, Pages 2492-2501

Publisher

MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMcp1104080

Keywords

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Funding

  1. Vertex
  2. InterMune
  3. Johnson Johnson
  4. Boehringer Ingelheim
  5. Takeda and its Millennium Division

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A 50-year-old woman with bipolar depression presents with a widespread pruritic rash of 1 day's duration. She is afebrile and otherwise well. She has a history of childhood eczema and is allergic to sulfonamide antibiotics. Her medications include thyroxine daily, naproxen intermittently, and lamotrigine, which she began taking 3 weeks earlier. How should this case be evaluated and treated?

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