4.6 Article

Neurologic Findings of Craniovertebral Junction Disease

Journal

NEUROSURGERY
Volume 66, Issue 3, Pages A13-A21

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1227/01.NEU.0000365801.87711.60

Keywords

Bell's cruciate paralysis; Central cord syndrome; Chiari malformation; Craniovertebral junction syndromes; Posterior circulation ischemia

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IN THIS REVIEW, we explain the origins of central cord syndrome and Bell's cruciate paralysis and the intricate detail of neural pathways located in this region and their influence on motor and sensory function. Although lesion studies and tract tracing studies on primates over the past 50 years refute the theory of a somatotopically organized corticospinal tract, this concept continues to pervade many neuroanatomic texts. We categorized the various pathologies of the craniovertebral junction and their unique neurologic presentations. New developments in the fields of neuroscience of spinal tract lesioning are also discussed.

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