Journal
NEUROSCIENTIST
Volume 15, Issue 2, Pages 149-165Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/1073858408331372
Keywords
spinal cord injury; reorganization; behavioral recovery; sensorimotor pathways; adult neurogenesis
Categories
Funding
- NINDS NIH HHS [R01 NS048425-01A1, R01 NS048425] Funding Source: Medline
Ask authors/readers for more resources
Spinal cord injury research has greatly expanded in recent years, but our understanding of the mechanisms that underlie the functional recovery that can occur over the weeks and months following the initial injury, is far from complete. To grasp the scope of the problem, it is important to begin by defining the sensorimotor pathways that might be involved by a spinal injury. This is done in the rodent and nonhuman primate, which are two of the most commonly used animal models in basic and translational spinal injury research. Many of the better known experimentally induced models are then reviewed in terms of the pathways they involve and the reorganization and recovery that have been shown to follow. The better understood neuronal mechanisms mediating such post-injury plasticity, including dendritic spine growth and axonal sprouting, are then examined.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available