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Testing long-term memory in animal models of schizophrenia: Suggestions from CNTRICS

Journal

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
Volume 37, Issue 9, Pages 2141-2148

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.neubiorev.2013.06.005

Keywords

Episodic memory; Hippocampus; Mouse; Object recognition; Neuropsychiatric disease; Prefrontal cortex; Rat; Relational memory; Rodent; Paired-associate learning; Touchscreen

Funding

  1. Innovative Medicine Initiative Joint Undertaking [115008]
  2. European Union
  3. Medical Research Council [G0001354B, G1000183B, G0001354] Funding Source: researchfish

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This paper reports the results of discussions at the fourth meeting of Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) meeting, held over two days in Washington, DC in April 2011. The meeting focused on animal paradigms for assessing the cognitive constructs relevant to schizophrenia identified in previous CNTRICS meetings. This report focuses on the outcome of discussions in the general area of long-term memory. A number of candidate animal paradigms were discussed. Two of these - one for rodents and one for non-human primates - were recommended as particularly promising for further development. (C) 2013 Elsevier Ltd. All rights reserved.

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