Journal
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
Volume 34, Issue 4, Pages 528-532Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.neubiorev.2009.10.011
Keywords
Allodynia; Aninmal models; Mirror-image pain (MIP); Neuropathic pain
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Funding
- National Natural Science Foundation of China [30672020, 30600583]
- B. Braun Clinic Anesthesia Foundation of B. Braun Medical (Shanghai) International Trading Co., Ltd
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The contralateral allodynia to an injury has been described both in humans and various models of neuropathic and inflammatory pain in rats. In this article, the occurrence of mirror-image pain (MIP) in human beings and animals were reviewed and the possible mechanism of MIP reported was summarized. Last, according to the literature published, we raise some speculation about the possible mechanism underlying MIP. (C) 2009 Elsevier Ltd. All rights reserved.
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