4.7 Review

Muscarinic and Nicotinic Acetylcholine Receptor Agonists and Allosteric Modulators for the Treatment of Schizophrenia

Related references

Note: Only part of the references are listed.
Article Behavioral Sciences

A new automated method to assess the rat recognition memory: Validation of the method

Caroline Chambon et al.

BEHAVIOURAL BRAIN RESEARCH (2011)

Article Behavioral Sciences

Behavioral effects of PNU-282987, an alpha7 nicotinic receptor agonist, in mice

Paloma Vicens et al.

BEHAVIOURAL BRAIN RESEARCH (2011)

Article Neurosciences

Effects of an Alpha 7-Nicotinic Agonist on Default Network Activity in Schizophrenia

Jason R. Tregellas et al.

BIOLOGICAL PSYCHIATRY (2011)

Article Developmental Biology

Insights into the neurodevelopmental origin of schizophrenia from postmortem studies of prefrontal cortical circuitry

Monica Beneyto et al.

INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2011)

Article Pharmacology & Pharmacy

RG3487, a Novel Nicotinic alpha 7 Receptor Partial Agonist, Improves Cognition and Sensorimotor Gating in Rodents

Tanya L. Wallace et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)

Review Neurosciences

Modes and Models of Forebrain Cholinergic Neuromodulation of Cognition

Michael E. Hasselmo et al.

NEUROPSYCHOPHARMACOLOGY (2011)

Article Behavioral Sciences

The enhancement of contextual fear conditioning by ABT-418

Justin W. Kenney et al.

BEHAVIOURAL PHARMACOLOGY (2010)

Article Chemistry, Medicinal

Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators

Thomas M. Bridges et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)

Review Pharmacology & Pharmacy

Treating the Cognitive Deficits of Schizophrenia with Alpha4Beta2 Neuronal Nicotinic Receptor Agonists

Richard J. Radek et al.

CURRENT PHARMACEUTICAL DESIGN (2010)

Article Biochemistry & Molecular Biology

Differential Regulation of alpha 7 Nicotinic Receptor Gene (CHRNA7) Expression in Schizophrenic Smokers

Sharon Mexal et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2010)

Article Neurosciences

Functional Magnetic Resonance Imaging of Effects of a Nicotinic Agonist in Schizophrenia

Jason R. Tregellas et al.

NEUROPSYCHOPHARMACOLOGY (2010)

Article Multidisciplinary Sciences

The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner

Benoit Poulin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Psychiatry

Varenicline and P50 auditory gating in medicated schizophrenic patients: A pilot study

Merilyne C. Waldo et al.

PSYCHIATRY RESEARCH (2010)

Article Ophthalmology

TOXIC EFFECT OF SCOPOLAMINE EYE DROPS IN CHILDREN

B. HAMBORG-PETERSEN et al.

ACTA OPHTHALMOLOGICA (2009)

Article Pharmacology & Pharmacy

nAChR agonist-induced cognition enhancement: Integration of cognitive and neuronal mechanisms

Martin Sarter et al.

BIOCHEMICAL PHARMACOLOGY (2009)

Article Pharmacology & Pharmacy

Pharmacological comparison of muscarinic ligands: Historical versus more recent muscarinic M1-preferring receptor agonists

Julia N. Heinrich et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2009)

Article Pharmacology & Pharmacy

Desensitization of Nicotinic Acetylcholine Receptors as a Strategy for Drug Development

Jerry J. Buccafusco et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)

Article Pharmacology & Pharmacy

Procognitive and Neuroprotective Activity of a Novel α7 Nicotinic Acetylcholine Receptor Agonist for Treatment of Neurodegenerative and Cognitive Disorders

Renza Roncarati et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)

Article Biochemistry & Molecular Biology

Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia

E. Scarr et al.

MOLECULAR PSYCHIATRY (2009)

Review Biotechnology & Applied Microbiology

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

P. Jeffrey Conn et al.

NATURE REVIEWS DRUG DISCOVERY (2009)

Review Physiology

Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function

Edson X. Albuquerque et al.

PHYSIOLOGICAL REVIEWS (2009)

Article Multidisciplinary Sciences

Selective activation of the M1 muscarinic acetylcholine receptor achieved by allosteric potentiation

Lei Ma et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Review Clinical Neurology

Effect of R3487/MEM3454, a novel nicotinic α7 receptor partial agonist and 5-HT3 antagonist on sustained attention in rats

Amir H. Rezvani et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2009)

Review Psychiatry

The Dopamine Hypothesis of Schizophrenia: Version III - The Final Common Pathway

Oliver D. Howes et al.

SCHIZOPHRENIA BULLETIN (2009)

Article Psychiatry

Prepulse inhibition deficits in schizophrenia are modified by smoking status

Andrea A. Woznica et al.

SCHIZOPHRENIA RESEARCH (2009)

Article Psychiatry

Weight effects associated with antipsychotics: A comprehensive database analysis

Bruce Parsons et al.

SCHIZOPHRENIA RESEARCH (2009)

Article Psychiatry

Initial phase 2 trial of a nicotinic agonist in schizophrenia

Robert Freedman et al.

AMERICAN JOURNAL OF PSYCHIATRY (2008)

Article Psychiatry

Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia

Anantha Shekhar et al.

AMERICAN JOURNAL OF PSYCHIATRY (2008)

Article Pharmacology & Pharmacy

Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77-LH-28-1

C. J. Langmead et al.

BRITISH JOURNAL OF PHARMACOLOGY (2008)

Article Biochemical Research Methods

Functional selectivity in GPCR modulator screening

Terry Kenakin

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2008)

News Item Medicine, General & Internal

FDA warns of adverse events linked to smoking cessation drug and antiepileptics

Bridget M. Kuehn

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2008)

Article Pharmacology & Pharmacy

Centrally Active Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Rats

Ashley E. Brady et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)

Article Multidisciplinary Sciences

Large recurrent microdeletions associated with schizophrenia

Hreinn Stefansson et al.

NATURE (2008)

Article Multidisciplinary Sciences

Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia

W. Y. Chan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Health Policy & Services

What CATIE found: Results from the schizophrenia trial

Marvin S. Swartz et al.

PSYCHIATRIC SERVICES (2008)

Article Biochemistry & Molecular Biology

An allosteric potentiator of M-4 mAChR modulates hippocampal synaptic transmission

Jana K. Shirey et al.

NATURE CHEMICAL BIOLOGY (2008)

Article Pharmacology & Pharmacy

An allosteric modulator of the α7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo

Daniel B. Timmermann et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)

Article Pharmacology & Pharmacy

Distinct profiles of α7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes

Jens Halvard Gronlien et al.

MOLECULAR PHARMACOLOGY (2007)

Article Neurosciences

Evaluation of N-desmethylclozapine as a potential antipsychotic -: Preclinical studies

Sridhar Natesan et al.

NEUROPSYCHOPHARMACOLOGY (2007)

Article Multidisciplinary Sciences

Nootropic α7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators

Herman J. Ng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Psychiatry

Early onset of treatment effects with oral risperidone

Thomas J. Raedler et al.

BMC PSYCHIATRY (2007)

Review Biotechnology & Applied Microbiology

Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development

Juergen Wess et al.

NATURE REVIEWS DRUG DISCOVERY (2007)

Article Pharmacology & Pharmacy

Varenicline is a partial agonist at α4β2 and a full agonist at α7 neuronal nicotinic receptors

Karla B. Mihalak et al.

MOLECULAR PHARMACOLOGY (2006)

Article Psychiatry

Proof-of-concept trial of an α7 nicotinic agonist in schizophrenia

Ann Olincy et al.

ARCHIVES OF GENERAL PSYCHIATRY (2006)

Article Neurosciences

Effects of nicotine nasal spray on cognitive function in schizophrenia

RC Smith et al.

NEUROPSYCHOPHARMACOLOGY (2006)

Article Neurosciences

Decreased density of muscarinic receptors in the superior temporal gyrus in schizophrenia

C Deng et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2005)

Article Psychiatry

Evidence for onset of antipsychotic effects within the first 24 hours of treatment

S Kapur et al.

AMERICAN JOURNAL OF PSYCHIATRY (2005)

Article Pharmacology & Pharmacy

Pharmacologic interactions between the muscarinic cholinergic and dopaminergic systems in the modulation of prepulse inhibition in rats

CK Jones et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)

Review Pharmacology & Pharmacy

Effects of nicotinic stimulation on cognitive performance

PA Newhouse et al.

CURRENT OPINION IN PHARMACOLOGY (2004)

Article Psychiatry

Identification of separable cognitive factors in schizophrenia

KH Nuechterlein et al.

SCHIZOPHRENIA RESEARCH (2004)

Review Neurosciences

Neuronal nicotinic receptors: from structure to pathology

C Gotti et al.

PROGRESS IN NEUROBIOLOGY (2004)

Article Neurosciences

Effects of nicotine on cognitive deficits in schizophrenia

JG Harris et al.

NEUROPSYCHOPHARMACOLOGY (2004)

Article Psychiatry

Delayed-onset hypothesis of antipsychotic action - A hypothesis tested and rejected

O Agid et al.

ARCHIVES OF GENERAL PSYCHIATRY (2003)

Article Multidisciplinary Sciences

N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl-D-aspartate receptor activity

C Sur et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Neurosciences

Role for M5 muscarinic acetylcholine receptors in cocaine addiction

A Fink-Jensen et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2003)

Article Neurosciences

Attentional effects of nicotinic agonists in rats

B Hahn et al.

NEUROPHARMACOLOGY (2003)

Article Genetics & Heredity

Reduced expression of the muscarinic 1 receptor cortical subtype in schizophrenia

D Mancama et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2003)

Article Neurosciences

Selective cognitive dysfunction in acetylcholine M-1 muscarinic receptor mutant mice

SG Anagnostaras et al.

NATURE NEUROSCIENCE (2003)

Article Psychiatry

In vivo determination of muscarinic acetylcholine receptor availability in schizophrenia

TJ Raedler et al.

AMERICAN JOURNAL OF PSYCHIATRY (2003)

Article Neurosciences

Dementia rating and nicotinic receptor expression in the prefrontal cortex in schizophrenia

CM Martin-Ruiz et al.

BIOLOGICAL PSYCHIATRY (2003)

Article Neurosciences

Nicotinic receptor subtypes and cognitive function

ED Levin

JOURNAL OF NEUROBIOLOGY (2002)

Article Multidisciplinary Sciences

Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia

AS Basile et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Letter Psychiatry

Effects of NMDA receptor antagonists: Implications for the pathophysiology of schizophrenia

JH Krystal et al.

ARCHIVES OF GENERAL PSYCHIATRY (2002)

Article Pharmacology & Pharmacy

Discovery of an ectopic activation site on the M1 muscarinic receptor

TA Spalding et al.

MOLECULAR PHARMACOLOGY (2002)

Review Clinical Neurology

Brain-selective stimulation of nicotinic receptors by TC-1734 enhances ACh transmission from frontoparietal cortex and memory in rodents

MC Obinu et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2002)

Article Biochemistry & Molecular Biology

Decreased muscarinic(1) receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia

B Dean et al.

MOLECULAR PSYCHIATRY (2002)

Article Multidisciplinary Sciences

Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient mice

DJ Gerber et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Multidisciplinary Sciences

Cholinergic dilation of cerebral blood vessels is abolished in M5 muscarinic acetylcholine receptor knockout mice

M Yamada et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia

A Marutle et al.

JOURNAL OF CHEMICAL NEUROANATOMY (2001)

Article Multidisciplinary Sciences

Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean

M Yamada et al.

NATURE (2001)

Article Psychiatry

Physostigmine and cognition in schizotypal personality disorder

RM Kirrane et al.

SCHIZOPHRENIA RESEARCH (2001)

Article Neurosciences

Cognitive effects of nicotine

AH Rezvani et al.

BIOLOGICAL PSYCHIATRY (2001)

Article Neurosciences

Abnormal regulation of high affinity nicotinic receptors in subjects with schizophrenia

CR Breese et al.

NEUROPSYCHOPHARMACOLOGY (2000)

Article Pharmacology & Pharmacy

Presynaptic nicotinic receptors modulating dopamine release in the rat striatum

S Wonnacott et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2000)