Journal
NEUROPATHOLOGY
Volume 30, Issue 2, Pages 189-193Publisher
WILEY
DOI: 10.1111/j.1440-1789.2009.01088.x
Keywords
ALS; amyotrophic lateral sclerosis; Golgi apparatus; pathology; review
Categories
Funding
- Ministry of Health, Labour and Welfare of Japan
- Ministry of Education, Culture, Sports, Science and Technology of Japan
Ask authors/readers for more resources
Protein synthesis and degradation systems in neurons are among the major subjects of study in neurobiology. These systems are believed to be the main pathways involved in ALS; however, the essential pathomechanisms that underlie this disease remain obscure. In addition to the ubiquitin-proteasomal and autophagic systems, several cytoplasmic organelles are also involved in ALS. Here, we present our data and discuss the main morphological abnormalities detected in the anterior horn cells of ALS patients.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available