Journal
NEURON
Volume 77, Issue 6, Pages 1017-1038Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2013.03.008
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Funding
- NINDS NIH HHS [R01-NS39600, R01 NS039600] Funding Source: Medline
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The importance of neuronal morphology in brain function has been recognized for over a century. The broad applicability of digital reconstructions of neuron morphology across neuroscience subdisciplines has stimulated the rapid development of numerous synergistic tools for data acquisition, anatomical analysis, three-dimensional rendering, electrophysiological simulation, growth models, and data sharing. Here we discuss the processes of histological labeling, microscopic imaging, and semiautomated tracing. Moreover, we provide an annotated compilation of currently available resources in this rich research ecosystem as a central reference for experimental and computational neuroscience.
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