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Visceral Influences on Brain and Behavior

Journal

NEURON
Volume 77, Issue 4, Pages 624-638

Publisher

CELL PRESS
DOI: 10.1016/j.neuron.2013.02.008

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Funding

  1. Wellcome Trust
  2. Dr. Mortimer and Theresa Sackler Foundation

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Mental processes and their neural substrates are intimately linked to the homeostatic control of internal bodily state. There are a set of distinct interoceptive pathways that directly and indirectly influence brain functions. The anatomical organization of these pathways and the psychological/behavioral expressions of their influence appear along discrete, evolutionarily conserved dimensions that are tractable to a mechanistic understanding. Here, we review the role of these pathways as sources of biases to perception, cognition, emotion, and behavior and arguably the dynamic basis to the concept of self.

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