4.8 Article

GENSAT BAG Cre-Recombinase Driver Lines to Study the Functional Organization of Cerebral Cortical and Basal Ganglia Circuits

Journal

NEURON
Volume 80, Issue 6, Pages 1368-1383

Publisher

CELL PRESS
DOI: 10.1016/j.neuron.2013.10.016

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Funding

  1. NIMH IRP [MH002497-24]
  2. GENSAT [NIH/NINDS N271200723701C]
  3. NIH/NINDS MMRRC [201224636]
  4. NIH/NIDA [1P30 DA035756-01]
  5. NIH/NIMH [P50 MH090963 P2]
  6. Howard Hughes Medical Institute

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Recent development of molecular genetic techniques are rapidly advancing understanding of the functional role of brain circuits in behavior. Critical to this approach is the ability to target specific neuron populations and circuits. The collection of over 250 BAC Cre-recombinase driver lines produced by the GENSAT project provides a resource for such studies. Here we provide characterization of GENSAT BAG-Cre driver lines with expression in specific neuroanatomical pathways within the cerebral cortex and basal ganglia.

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