Journal
NEURON
Volume 77, Issue 3, Pages 379-381Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2013.01.023
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Funding
- NIH HHS [DP1 OD003889] Funding Source: Medline
- NIMH NIH HHS [DP1 MH099904, R33 MH087898, R21 MH087898] Funding Source: Medline
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Whether neurons generated in vitro from human embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) have in vivo-like properties is unknown. In this issue of Neuron, Espuny-Camacho et al. (2013) show that ESC-/iPSC-derived cortical neurons make specific projections and functional synapses when transplanted into a neonatal mouse brain.
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