Journal
NEURON
Volume 73, Issue 3, Pages 405-407Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2012.01.009
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In this issue of Neuron, Hu et al. (2012) report that upon axonal damage, CHOP and XBP1 unfolded protein response pathways are not recruited equally and have opposite effects on neuronal survival. XBP1 pathway boosting may represent a valuable neuroprotective strategy.
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