Journal
NEURON
Volume 70, Issue 3, Pages 410-426Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2011.04.009
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Funding
- NIH [AG011385, NS041787]
- Tau Consortium
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While the microtubule-binding capacity of the protein tau has been known for many years, new functions of tau in signaling and cytoskeletal organization have recently emerged. In this review, we highlight these functions and the potential roles of tau in neurodegenerative disease. We also discuss the therapeutic potential of drugs targeting various aspects of tau biology.
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