Journal
NEURON
Volume 68, Issue 2, Pages 254-269Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2010.10.004
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Funding
- NIMH NIH HHS [RC2 MH089956, RC2 MH089956-02, R01 MH092289-01A1, R01 MH092289] Funding Source: Medline
- NINDS NIH HHS [R01 NS056276-05, R01 NS056276] Funding Source: Medline
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Investigations into the genetics of child psychiatric disorders have finally begun to shed light on molecular and cellular mechanisms of psychopathology. The first strains of success in this notoriously difficult area of inquiry are the result of an increasingly sophisticated appreciation of the allelic architecture of common neuropsychiatric and neurodevelopmental disorders, the consolidation of large patient cohorts now beginning to reach sufficient size to power reliable studies, the emergence of genomic tools enabling comprehensive investigations of rare as well as common genetic variation, and advances in developmental neuroscience that are fueling the rapid translation of genetic findings.
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