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Neurons that Fire Together Also Conspire Together: Is Normal Sleep Circuitry Hijacked to Generate Epilepsy?

Journal

NEURON
Volume 62, Issue 5, Pages 612-632

Publisher

CELL PRESS
DOI: 10.1016/j.neuron.2009.05.015

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Funding

  1. NIH/NINDS [34774, 07280]

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Brain circuits oscillate during sleep. The same circuits appear to generate pathological oscillations. In this review, we discuss recent advances in our understanding of how epilepsy co-opts normal, sleep-related circuits to generate seizures.

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