Journal
NEURON
Volume 60, Issue 3, Pages 477-482Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2008.10.020
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Funding
- NIMH NIH HHS [R01 MH066338] Funding Source: Medline
- NINDS NIH HHS [R01 NS036853] Funding Source: Medline
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The remarkable versatility of the mammalian brain is made possible by a huge diversity of cellular plasticity mechanisms. These include long-term potentiation and depression at both excitatory and inhibitory synapses, as well as a variety of intrinsic and homeostatic plasticity mechanisms. A fundamental challenge for the field is to assemble our detailed knowledge of these specific mechanisms into a coherent picture of how plasticity within cortical circuits works to tune network properties.
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