Journal
NEURON
Volume 57, Issue 4, Pages 477-479Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2008.02.004
Keywords
-
Categories
Ask authors/readers for more resources
While Trk receptors can be activated in a neurotrophin-independent manner through transactivation by GPCR ligands, its physiological significance in the brain remains unknown. Huang et al. have now identified a novel mechanism of TrkB transactivation. They show that zinc ions can transactivate TrkB independent of neurotrophins and that such a transactivation is important for mossy fiber long-term potentiation (LTP).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available