Synthesis, characterization and study of antioxidant activity of quercetin-magnesium complex

Quercetin (3,3',4',5,7-pentahydroxyflavone) one of the most abundant dietary flavonoids, has been investigated in the presence of magnesium (II) in methanol. The complex formation between quercetin and magnesium (II) was examined under UV-visible, Infra-red and H-1 NMR spectroscopic techniques. The spectroscopic data denoted that quercetin can reacts with magnesium cation (Mg+2) through the chelation site in the quercetin molecule. The free radical antioxidant activity of the complex with respect to the parent molecule was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. It was observed that the free radical scavenging activity of quercetin was increased after complexation of magnesium (Me+2) cation. (C) 2015 Elsevier B.V. All rights reserved.