Journal
NEUROLOGICAL SCIENCES
Volume 31, Issue -, Pages 245-248Publisher
SPRINGER-VERLAG ITALIA SRL
DOI: 10.1007/s10072-010-0370-x
Keywords
MRI; Cognition; Brain atrophy; MR spectroscopy
Categories
Ask authors/readers for more resources
The overall burden of brain MRI-visible lesions does not fully account for cognitive impairment in multiple sclerosis (MS). Several MRI studies have highlighted the importance of brain damage in the normal-appearing brain tissue. Brain atrophy (global, cortical, white and deep grey matter) is related to cognitive deficits in MS patients and this holds true since the earliest disease stages. Non-conventional MRI techniques such as proton MR spectroscopy have related metabolic changes in specific brain areas to specific cognitive deficits. Overall, data provided by MRI support the notion that cognitive disturbances need to be considered for a more complete clinical characterisation of patients with MS, including those with benign MS.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available