Journal
NEUROLOGICAL RESEARCH
Volume 35, Issue 10, Pages 1092-1102Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1179/1743132813Y.0000000250
Keywords
MRI; PET; Diffusion; Perfusion; Cerebral blood flow; Cerebral ischemia; Blood-brain barrier; Functional MRI
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Funding
- NCATS NIH HHS [UL1 TR001120, KL2 TR001118] Funding Source: Medline
- NINDS NIH HHS [R01 NS045879] Funding Source: Medline
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Stroke is a serious healthcare problem with high mortality and long-term disability. However, to date, our ability to prevent and cure stroke remains limited. One important goal in stroke research is to identify the extent and location of lesion for treatment. In addition, accurately differentiating salvageable tissue from infarct and evaluating therapeutic efficacies are indispensible. These objectives could potentially be met with the assistance of modern neuroimaging techniques. This paper reviews current imaging methods commonly used in ischemic stroke research. These methods include positron emission tomography, computed tomography, T1 MRI, T2 MRI, diffusion and perfusion MRI, diffusion tensor imaging, blood-brain barrier permeability MRI, pH-weighted MRI, and functional MRI.
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