Journal
NEUROLOGIC CLINICS
Volume 32, Issue 1, Pages 253-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ncl.2013.07.008
Keywords
Magnetic resonance imaging; Focused ultrasound; Neurosurgery; Brain tumor; Targeted drug delivery; Chemotherapy; Neuromodulation; Blood-brain-barrier
Categories
Funding
- NIH [P41 EB015898, P01CA067165, R01EB003268, R33EB000705, RC2NS69413]
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Transcranial MRI-guided focused ultrasound (TcMRgFUS) is an old idea but a new technology that may change the entire clinical field of the neurosciences. TcMRgFUS has no cumulative effect, and it is applicable for repeatable treatments, controlled by real-time dosimetry, and capable of immediate tissue destruction. Most importantly, it has extremely accurate targeting and constant monitoring. It is potentially more precise than proton beam therapy and definitely more cost effective. Neuro-oncology may be the most promising area of future TcMRgFUS applications.
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