Journal
NEUROIMAGING CLINICS OF NORTH AMERICA
Volume 23, Issue 3, Pages 425-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.nic.2012.12.013
Keywords
Hypomyelination; Leukodystrophy; Leukoencephalopathy; Metabolic diseases; MR spectroscopy; White matter
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Magnetic resonance spectroscopy (MRS) is a powerful clinical tool for investigating the metabolic characteristics of neurologic diseases. Proton (H-1)-MRS is the most commonly used and widely available method. In this article, a brief introduction regarding technical issues of H-1-MRS applied to the study of metabolic diseases is followed by a description of findings in some of the most common entities in this large, heterogeneous group of neurologic disorders. The aim was to provide a focused representation of the most common applications of H-1-MRS to metabolic disorders in a routine clinical setting.
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