Journal
NEUROIMAGE
Volume 64, Issue -, Pages 416-424Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2012.09.023
Keywords
Phase/amplitude coupling; Cross-frequency coupling; Electrophysiology; Electrocorticography; Theta; Alpha; Gamma
Funding
- American Psychological Association Diversity Program in Neuroscience [5-T32-MH18882]
- NINDS [NS21135, NS40596, PO40813]
- NATIONAL INSTITUTE OF MENTAL HEALTH [T32MH018882] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [P01NS040813, R01NS040596, R01NS021135, R37NS021135, R56NS021135] Funding Source: NIH RePORTER
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Phase/amplitude coupling (PAC) is emerging as an important electrophysiological measure of local and long-distance neuronal communication. Current techniques for calculating PAC provide a numerical index that represents an average value across an arbitrarily long time period. This requires researchers to rely on block design experiments and temporal concatenation at the cost of the sub-second temporal resolution afforded by electrophysiological recordings. Here we present a method for calculating event-related phase/amplitude coupling (ERPAC) designed to capture the temporal evolution of task-related changes in PAC across events or between distant brain regions that is applicable to human or animal electromagnetic recording. (C) 2012 Elsevier Inc. All rights reserved.
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