Journal
NEUROEPIDEMIOLOGY
Volume 36, Issue 1, Pages 52-61Publisher
KARGER
DOI: 10.1159/000322942
Keywords
Alzheimer's disease; Dementia; Randomized controlled trial; Study design; Counselling; Psychosocial intervention; Support; Caregiving
Funding
- National Board of Social Services at the Ministry of Social Affairs
- Ministry of Health
- Danish Health Foundation
- Research council of the Copenhagen Hospital Cooperation
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Background: There is a lack of appropriately designed trials investigating the efficacy of psychosocial interventions for patients with mild dementia and their family caregivers. This paper reports the rationale and design of the Danish Alzheimer Disease Intervention Study and baseline characteristics of the cohort. Methods: The study was a 1-year multicentre randomized controlled rater-blinded trial with randomization to follow-up and a multifaceted semitailored intervention programme or to follow-up only (with extension of follow-up to 3 years). The intervention included a counselling programme, teaching courses, written information and logbooks. The outcomes included clinical efficacy parameters, patient satisfaction and health economic consequences. Results: A total of 330 patients and their 330 caregivers were included during a period of 18 months. The majority (65.2 %) of the caregivers were spouses. At inclusion the mean age of the patients and caregivers was 76.2 and 66.0 years, respectively. Conclusion: The study will explore the added value of a multifaceted intervention programme and contribute to the design of future interventions for patients with mild dementia and their caregivers. Copyright (C) 2010 S. Karger AG, Basel
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