Electrical parameters influence on the dynamics of the Hodgkin-Huxley liquid state machine

The model of mammalian cortical hypercolumn was simulated using liquid state machines built of simple Hodgkin-Huxley neurons. The influence of cell electrical parameters on the system dynamics was investigated. The systematic analysis of the hypercolumn separation ability in the function of time constants, cell membrane capacitance, resistance, Hodgkin-Huxley equilibrium potential and sodium and potassium channel conductances was performed. Optimal ranges of time constants for the most effective computational abilities of the model were estimated. (C) 2011 Elsevier B.V. All rights reserved.