EvOL-NEURON: Neuronal morphology generation

Virtual neurons are essential in computational neuroscience to study the relation between neuronal form and function. One way of obtaining virtual neurons is by algorithmic generation from scratch. However, a main disadvantage of current available generation methods is that they impose a priori limitations on the outcomes of the algorithms. We present a new tool, EvOL-NEURON, that overcomes this problem by putting a posteriori constraints on generated virtual neurons. We present a proof of principle and show that our method is particularly suited to investigate the neuronal form-function relation. (c) 2007 Elsevier B.V. All rights reserved.