Journal
NEUROCHIRURGIE
Volume 67, Issue 1, Pages 6-13Publisher
MASSON EDITEUR
DOI: 10.1016/j.neuchi.2017.10.003
Keywords
Medulloblastoma; Imaging; MRI; Subtypes; Perfusion-weighted imaging; Diffusion-weighted imaging; Proton spectroscopy; Follow-up; Child; Brain tumour
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The study reviews the classical and atypical imaging features of medulloblastomas, emphasizing on advanced MRI techniques, histopathological and molecular subtypes, as well as follow-up modalities. Atypical imaging features have been widely reported, varying according to the age of the patient and histopathological subtype.
Medulloblastoma is a frequent high-grade neoplasm among pediatric brain tumours. Its classical imaging features are a midline tumour growing into the fourth ventricle, hyperdense on CT-scan, displaying a hypersignal when using diffusion-weighted imaging, with a variable contrast enhancement. Nevertheless, atypical imaging features have been widely reported, varying according to the age of the patient, and histopathological subtype. In this study, we review the classical and atypical imaging features of medulloblastomas, with emphasis on advanced MRI techniques, histopathological and molecular subtypes and characteristics, and follow-up modalities. (c) 2017 Elsevier Masson SAS. All rights reserved.
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