Related references
Note: Only part of the references are listed.Genetic animal models for evaluating the role of autophagy in etiopathogenesis of Parkinson disease
M. Lenard Lachenmayer et al.
AUTOPHAGY (2012)
Re-examination of the dimerization state of leucine-rich repeat kinase 2: predominance of the monomeric form
Genta Ito et al.
BIOCHEMICAL JOURNAL (2012)
The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation
Iakov N. Rudenko et al.
BIOCHEMICAL JOURNAL (2012)
The GTPase function of LRRK2
Jean-Marc Taymans
BIOCHEMICAL SOCIETY TRANSACTIONS (2012)
Number and Brightness Analysis of LRRK2 Oligomerization in Live Cells
Nicholas G. James et al.
BIOPHYSICAL JOURNAL (2012)
(G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD
C-Y Chen et al.
CELL DEATH AND DIFFERENTIATION (2012)
Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences
Nicole Exner et al.
EMBO JOURNAL (2012)
Targeting intracellular and extracellular alpha-synuclein as a therapeutic strategy in Parkinson's disease and other synucleinopathies
Kostas Vekrellis et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2012)
LRRK2 Parkinson disease mutations enhance its microtubule association
Lauren R. Kett et al.
HUMAN MOLECULAR GENETICS (2012)
Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP
Patricia Gomez-Suaga et al.
HUMAN MOLECULAR GENETICS (2012)
Neurodegenerative phenotypes in an A53T-synuclein transgenic mouse model are independent of LRRK2
Joao Paulo L. Daher et al.
HUMAN MOLECULAR GENETICS (2012)
LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6
Daniel C. Berwick et al.
HUMAN MOLECULAR GENETICS (2012)
G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization
Tatiana D. Papkovskaia et al.
HUMAN MOLECULAR GENETICS (2012)
LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1
Xinglong Wang et al.
HUMAN MOLECULAR GENETICS (2012)
ArfGAP1 Is a GTPase Activating Protein for LRRK2: Reciprocal Regulation of ArfGAP1 by LRRK2
Yulan Xiong et al.
JOURNAL OF NEUROSCIENCE (2012)
LRRK2 Inhibition Attenuates Microglial Inflammatory Responses
Mark S. Moehle et al.
JOURNAL OF NEUROSCIENCE (2012)
Disrupted Autophagy Leads to Dopaminergic Axon and Dendrite Degeneration and Promotes Presynaptic Accumulation of α-Synuclein and LRRK2 in the Brain
Lauren G. Friedman et al.
JOURNAL OF NEUROSCIENCE (2012)
The I2020T Leucine-rich repeat kinase 2 transgenic mouse exhibits impaired locomotive ability accompanied by dopaminergic neuron abnormalities
Tatsunori Maekawa et al.
MOLECULAR NEURODEGENERATION (2012)
Exosomal cell-to-cell transmission of alpha synuclein oligomers
Karin M. Danzer et al.
MOLECULAR NEURODEGENERATION (2012)
LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis
Samer Matta et al.
NEURON (2012)
PARKINSON'S DISEASE-LINKED LEUCINE-RICH REPEAT KINASE 2(R1441G) MUTATION INCREASES PROINFLAMMATORY CYTOKINE RELEASE FROM ACTIVATED PRIMARY MICROGLIAL CELLS AND RESULTANT NEUROTOXICITY
F. Gillardon et al.
NEUROSCIENCE (2012)
LRRK2 I2020T mutation is associated with tau pathology
Sachiko Ujiie et al.
PARKINSONISM & RELATED DISORDERS (2012)
LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth
Fumitaka Kawakami et al.
PLOS ONE (2012)
A Cell Permeable Peptide Inhibitor of NFAT Inhibits Macrophage Cytokine Expression and Ameliorates Experimental Colitis
Houda Z. Elloumi et al.
PLOS ONE (2012)
High LRRK2 Levels Fail to Induce or Exacerbate Neuronal Alpha-Synucleinopathy in Mouse Brain
Martin C. Herzig et al.
PLOS ONE (2012)
The IkappaB Kinase Family Phosphorylates the Parkinson's Disease Kinase LRRK2 at Ser935 and Ser910 during Toll-Like Receptor Signaling
Nicolas Dzamko et al.
PLOS ONE (2012)
Biochemical Characterization of Highly Purified Leucine-Rich Repeat Kinases 1 and 2 Demonstrates Formation of Homodimers
Laura Civiero et al.
PLOS ONE (2012)
Phosphorylation of 4E-BP1 in the Mammalian Brain Is Not Altered by LRRK2 Expression or Pathogenic Mutations
Alzbeta Trancikova et al.
PLOS ONE (2012)
Ser1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations
Zejuan Sheng et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease
Oliver Cooper et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
GTPase Activity and Neuronal Toxicity of Parkinson's Disease-Associated LRRK2 Is Regulated by ArfGAP1
Klodjan Stafa et al.
PLOS GENETICS (2012)
α-Synuclein Aggregation and Transmission Are Enhanced by Leucine-Rich Repeat Kinase 2 in Human Neuroblastoma SH-SY5Y Cells
Kazunari Kondo et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2011)
Hyperphosphorylated Tau in an α-synuclein-overexpressing transgenic model of Parkinson's disease
Thomas Haggerty et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2011)
JNK regulates FoxO-dependent autophagy in neurons
Ping Xu et al.
GENES & DEVELOPMENT (2011)
LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice
Martin C. Herzig et al.
HUMAN MOLECULAR GENETICS (2011)
Meta-analysis of Published Studies Identified Eight Additional Common Susceptibility Loci for Crohn's Disease and Ulcerative Colitis
Junji Umeno et al.
INFLAMMATORY BOWEL DISEASES (2011)
Temporal Expression of Mutant LRRK2 in Adult Rats Impairs Dopamine Reuptake
Hongxia Zhou et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2011)
Autophosphorylation in the Leucine-Rich Repeat Kinase 2 (LRRK2) GTPase Domain Modifies Kinase and GTP-Binding Activities
Philip J. Webber et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures
Mansoureh Hakimi et al.
JOURNAL OF NEURAL TRANSMISSION (2011)
Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant
Veronique Daniels et al.
JOURNAL OF NEUROCHEMISTRY (2011)
A Rat Model of Progressive Nigral Neurodegeneration Induced by the Parkinson's Disease-Associated G2019S Mutation in LRRK2
Julien Dusonchet et al.
JOURNAL OF NEUROSCIENCE (2011)
LRRK2 Controls Synaptic Vesicle Storage and Mobilization within the Recycling Pool
Giovanni Piccoli et al.
JOURNAL OF NEUROSCIENCE (2011)
Inhibition of Cyclin-Dependent Kinase 5 but Not of Glycogen Synthase Kinase 3-β Prevents Neurite Retraction and Tau Hyperphosphorylation Caused by Secretable Products of Human T-Cell Leukemia Virus Type I-Infected Lymphocytes
Horacio Maldonado et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2011)
Pathological roles of α-synuclein in neurological disorders (vol 10, pg 1015, 2011)
K. Vekrellis et al.
LANCET NEUROLOGY (2011)
The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease
Zhihua Liu et al.
NATURE IMMUNOLOGY (2011)
Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
B. Winner et al.
NEUROBIOLOGY OF DISEASE (2011)
Role of Mendelian genes in “sporadic” Parkinson's disease
Suzanne Lesage et al.
PARKINSONISM & RELATED DISORDERS (2011)
Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2
David Ramonet et al.
PLOS ONE (2011)
Leucine-Rich Repeat Kinase 2 Modulates Retinoic Acid-Induced Neuronal Differentiation of Murine Embryonic Stem Cells
Cathrin Schulz et al.
PLOS ONE (2011)
LRRK2 Kinase Activity Is Dependent on LRRK2 GTP Binding Capacity but Independent of LRRK2 GTP Binding
Jean-Marc Taymans et al.
PLOS ONE (2011)
Pathological roles of α-synuclein in neurological disorders
Kostas Vekrellis et al.
LANCET NEUROLOGY (2011)
Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization
Nicolas Dzamko et al.
BIOCHEMICAL JOURNAL (2010)
14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
R. Jeremy Nichols et al.
BIOCHEMICAL JOURNAL (2010)
Membrane Localization of LRRK2 Is Associated with Increased Formation of the Highly Active LRRK2 Dimer and Changes in Its Phosphorylation
Zdenek Berger et al.
BIOCHEMISTRY (2010)
Mechanisms in dominant parkinsonism: The toxic triangle of LRRK2, α-synuclein, and tau
Jean-Marc Taymans et al.
BIOESSAYS (2010)
Leucine-rich repeat kinase 2 induces α-synuclein expression via the extracellular signal-regulated kinase pathway
Iria Carballo-Carbajal et al.
CELLULAR SIGNALLING (2010)
Complex I: Inhibitors, inhibition and neurodegeneration
A. H. V. Schapira
EXPERIMENTAL NEUROLOGY (2010)
Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila
Tomoko Kanao et al.
HUMAN MOLECULAR GENETICS (2010)
LRRK2 Is Involved in the IFN-γ Response and Host Response to Pathogens
Agnes Gardet et al.
JOURNAL OF IMMUNOLOGY (2010)
Enhanced Striatal Dopamine Transmission and Motor Performance with LRRK2 Overexpression in Mice Is Eliminated by Familial Parkinson's Disease Mutation G2019S
Xianting Li et al.
JOURNAL OF NEUROSCIENCE (2010)
Phosphopeptide Analysis Reveals Two Discrete Clusters of Phosphorylation in the N-Terminus and the Roc Domain of the Parkinson-Disease Associated Protein Kinase LRRK2
Christian Johannes Gloeckner et al.
JOURNAL OF PROTEOME RESEARCH (2010)
Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease
Byoung Dae Lee et al.
NATURE MEDICINE (2010)
Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice
H. L. Melrose et al.
NEUROBIOLOGY OF DISEASE (2010)
Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2
Heather Mortiboys et al.
NEUROLOGY (2010)
The Parkinson's Disease Associated LRRK2 Exhibits Weaker In Vitro Phosphorylation of 4E-BP Compared to Autophosphorylation
Azad Kumar et al.
PLOS ONE (2010)
Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice
Youren Tong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
GTPase Activity Plays a Key Role in the Pathobiology of LRRK2
Yulan Xiong et al.
PLOS GENETICS (2010)
Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions
Elisa Greggio et al.
ASN NEURO (2009)
Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications
Hong Qing et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites
Elisa Greggio et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Down-regulation of FoxO-dependent c-FLIP expression mediates TRAIL-induced apoptosis in activated hepatic stellate cells
Soo-Jung Park et al.
CELLULAR SIGNALLING (2009)
Investigation of leucine-rich repeat kinase 2
Vasanti S. Anand et al.
FEBS JOURNAL (2009)
Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease
Katerina Venderova et al.
HUMAN MOLECULAR GENETICS (2009)
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
Javier Alegre-Abarrategui et al.
HUMAN MOLECULAR GENETICS (2009)
Caenorhabditits elegans LRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth
Julia Saermann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Dependence of Leucine-rich Repeat Kinase 2 (LRRK2) Kinase Activity on Dimerization
Saurabh Sen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability - a point of convergence in Parkinsonian neurodegeneration?
Frank Gillardon
JOURNAL OF NEUROCHEMISTRY (2009)
The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro
Christian Johannes Gloeckner et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Homo- and heterodimerization of ROCO kinases: LRRK2 kinase inhibition by the LRRK2 ROCO fragment
Christian L. Klein et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis
Loukia Parisiadou et al.
JOURNAL OF NEUROSCIENCE (2009)
Parkin Protects against LRRK2 G2019S Mutant-Induced Dopaminergic Neurodegeneration in Drosophila
Chee-Hoe Ng et al.
JOURNAL OF NEUROSCIENCE (2009)
Unexpected Lack of Hypersensitivity in LRRK2 Knock-Out Mice to MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine)
Eva Andres-Mateos et al.
JOURNAL OF NEUROSCIENCE (2009)
The Parkinson Disease Protein Leucine-Rich Repeat Kinase 2 Transduces Death Signals via Fas-Associated Protein with Death Domain and Caspase-8 in a Cellular Model of Neurodegeneration
Cherry Cheng-Ying Ho et al.
JOURNAL OF NEUROSCIENCE (2009)
Emerging role of LRRK2 in human neural progenitor cell cycle progression, survival and differentiation
Javorina Milosevic et al.
MOLECULAR NEURODEGENERATION (2009)
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
Wataru Satake et al.
NATURE GENETICS (2009)
Genome-wide association study reveals genetic risk underlying Parkinson's disease
Javier Simon-Sanchez et al.
NATURE GENETICS (2009)
Mutant LRRK2R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease
Yanping Li et al.
NATURE NEUROSCIENCE (2009)
Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein
Xian Lin et al.
NEURON (2009)
Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy
Maria Xilouri et al.
PLOS ONE (2009)
R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice
Youren Tong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila
Yuzuru Imai et al.
EMBO JOURNAL (2008)
LRRK2 regulates synaptic vesicle endocytosis
Narae Shin et al.
EXPERIMENTAL CELL RESEARCH (2008)
The Roco protein family:: a functional perspective
Ignacio Marin et al.
FASEB JOURNAL (2008)
Wild type α-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
Tereza Vogiatzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation
Elisa Greggio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis
Benno Weigmann et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
Edward D. Plowey et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Proteomics Analysis Identifies Phosphorylation-dependent α-Synuclein Protein Interactions
Melinda A. McFarland et al.
MOLECULAR & CELLULAR PROTEOMICS (2008)
Phosphorylation of tau and α-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer's disease, and in Parkinson's disease and related α-synucleinopathies
G. Muntane et al.
NEUROSCIENCE (2008)
Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease
M. Westerlund et al.
NEUROSCIENCE (2008)
Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase
Junpeng Deng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity
Mahaboobi Jaleel et al.
BIOCHEMICAL JOURNAL (2007)
Mutations in LRRK2/dardarin associated with Parkinson disease are more toxic than equivalent mutations in the homologous kinase LRRK1
Elisa Greggio et al.
JOURNAL OF NEUROCHEMISTRY (2007)
The R1441C mutation of LRRK2 disrupts GTP hydrolysis
Patrick A. Lewis et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs
Jong-Hwan Park et al.
JOURNAL OF IMMUNOLOGY (2007)
GTP binding is essential to the protein kinase activity of LRRK2, a causative gene product for familial Parkinson's disease
Genta Ito et al.
BIOCHEMISTRY (2007)
Neuropathology of Parkinson's disease associated with the LRRK2 Ile1371Val mutation
Maria Teresa Giordana et al.
MOVEMENT DISORDERS (2007)
Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain
Shinji Higashi et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Digenic parkinsonism:: Investigation of the synergistic effects of PRKN and LRRK2
Justus C. Dachsel et al.
NEUROSCIENCE LETTERS (2006)
The Parkinson disease gene LRRK2:: Evolutionary and structural insights
Ignacio Marin
MOLECULAR BIOLOGY AND EVOLUTION (2006)
Localization of LRRK2 to membranous and vesicular structures in mammalian brain
Saskia Biskup et al.
ANNALS OF NEUROLOGY (2006)
Kinase activity of mutant LRRK2 mediates neuronal toxicity
Wanli W. Smith et al.
NATURE NEUROSCIENCE (2006)
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
Elisa Greggio et al.
NEUROBIOLOGY OF DISEASE (2006)
A common missense variant in the LRRK2 gene, Gly2385Arg, associated with Parkinson's disease risk in Taiwan
Alessio Di Fonzo et al.
NEUROGENETICS (2006)
Mechanism of endophilin N-BAR domain-mediated membrane curvature
Jennifer L. Gallop et al.
EMBO JOURNAL (2006)
LRRK2 expression linked to dopamine-innervated areas
D Galter et al.
ANNALS OF NEUROLOGY (2006)
Anatomical localization of Leucine-rich repeat kinase 2 in mouse brain
H Melrose et al.
NEUROSCIENCE (2006)
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration
WW Smith et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
AB West et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
An LRRK2 mutation as a cause for the parkinsonism in the original PARK8 family
M Funayama et al.
ANNALS OF NEUROLOGY (2005)
Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism:: Evidence of a common founder across European populations
J Kachergus et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2005)
The RIP kinases: crucial integrators of cellular stress
E Meylan et al.
TRENDS IN BIOCHEMICAL SCIENCES (2005)
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
AM Cuervo et al.
SCIENCE (2004)
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
C Paisán-Ruíz et al.
NEURON (2004)
Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology
A Zimprich et al.
NEURON (2004)
RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF-κB and is processed during apoptosis
E Meylan et al.
EMBO REPORTS (2002)
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
K Kobayashi et al.
NATURE (2002)
A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13.1
M Funayama et al.
ANNALS OF NEUROLOGY (2002)
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
JP Hugot et al.
NATURE (2001)
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
Y Ogura et al.
NATURE (2001)
Caspase recruitment domain (CARD)-dependent cytoplasmic filaments mediate bcl10-induced NF-κB activation
C Guiet et al.
JOURNAL OF CELL BIOLOGY (2000)