4.6 Article

Imaging brain plasticity after trauma

Journal

NEURAL REGENERATION RESEARCH
Volume 9, Issue 7, Pages 693-700

Publisher

WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/1673-5374.131568

Keywords

traumatic brain injury; brain plasticity; neuroplasticity; neuroimaging; magnetic resonance imaging; fMRI; diffusion tensor imaging

Funding

  1. Department of Defense [W81X-WH-11-1-0493]

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The brain is highly plastic after stroke or epilepsy; however, there is a paucity of brain plasticity investigation after traumatic brain injury (TBI). This mini review summarizes the most recent evidence of brain plasticity in human TBI patients from the perspective of advanced magnetic resonance imaging. Similar to other forms of acquired brain injury, TBI patients also demonstrated both structural reorganization as well as functional compensation by the recruitment of other brain regions. However, the large scale brain network alterations after TBI are still unknown, and the field is still short of proper means on how to guide the choice of TBI rehabilitation or treatment plan to promote brain plasticity. The authors also point out the new direction of brain plasticity investigation.

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