3.9 Review

Regulation of Experimental Peritonitis: A Complex Orchestration

Journal

NEPHRON EXPERIMENTAL NEPHROLOGY
Volume 120, Issue 1, Pages E41-E46

Publisher

KARGER
DOI: 10.1159/000334169

Keywords

Experimental peritonitis; Macrophages; Lymphocytes; Mast cells; Leukocyte recruitment; Chemokines

Funding

  1. Kidney Foundation of Canada
  2. le Fonds de la recherche en sante du Quebec, la Fondation du CHUM
  3. Institut du Cancer de Montreal
  4. Fonds de la recherche en sante du Quebec
  5. J.L. Levesque Foundation
  6. CHUM renal division

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Experimental peritonitis is a frequently used inflammatory model to evaluate leukocyte recruitment. By the intrinsic characteristics of the peritoneal cavity, the various resident cell populations have a role to play in the initiation, the modulation and the resolution of peritoneal inflammation. Through various manipulations of these cell populations, we gained important knowledge on their respective roles in peritoneal inflammation. In this brief review, we will focus on the cellular regulation of leukocyte recruitment in experimental peritonitis. Copyright (C) 2012 S. Karger AG, Basel

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