Journal
NEPHROLOGY DIALYSIS TRANSPLANTATION
Volume 29, Issue 1, Pages 22-28Publisher
OXFORD UNIV PRESS
DOI: 10.1093/ndt/gft083
Keywords
renalase; sympathetic nervous system; hypertension; acute kidney injury; cardiovascular disease
Categories
Ask authors/readers for more resources
Renalase, a recently discovered flavoprotein, which is strongly expressed in the kidney and heart, effectively metabolizes catecholamines. It was discovered during the search to identify proteins secreted by the kidney that could help explain the high incidence of cardiovascular disease in patients with chronic kidney disease. Recent advances have led to more detailed knowledge of its biology, structure, enzymatic activity, mechanisms of action, associations with human disease states and potential therapeutic value. In this study, we review these advances with a focus on hypertension and kidney disease.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available