Journal
NEPHROLOGY DIALYSIS TRANSPLANTATION
Volume 24, Issue 9, Pages 2752-2754Publisher
OXFORD UNIV PRESS
DOI: 10.1093/ndt/gfp166
Keywords
anti-factor H antibodies; haemolytic uraemic syndrome; MCP mutation; varicella
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We report two cases of children who presented with haemolytic uraemic syndrome following varicella infection. One of them had a membrane cofactor protein mutation, and the other had anti-factor H antibodies. These observations show that infectious agents such as varicella-zoster virus may be the trigger of haemolytic uraemic syndrome in patients with complement dysregulation.
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