4.5 Article

Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Identification and functional characterization of zebrafish K2P10.1 (TREK2) two-pore-domain K+ channels

Jakob Gierten et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)

Article Pharmacology & Pharmacy

PKC-dependent activation of human K2P18.1 K+ channels

Ann-Kathrin Rahm et al.

BRITISH JOURNAL OF PHARMACOLOGY (2012)

Article Pharmacology & Pharmacy

TASK1 (K2P3.1) K+ channel inhibition by endothelin-1 is mediated through Rho kinase-dependent phosphorylation

C. Seyler et al.

BRITISH JOURNAL OF PHARMACOLOGY (2012)

Review Cardiac & Cardiovascular Systems

TREK-1 K+ Channels in the Cardiovascular System: Their Significance and Potential as a Therapeutic Target

Lakshman Goonetilleke et al.

CARDIOVASCULAR THERAPEUTICS (2012)

Article Multidisciplinary Sciences

Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K+ Ion Channel

Stephen G. Brohawn et al.

SCIENCE (2012)

Article Multidisciplinary Sciences

Crystal Structure of the Human Two-Pore Domain Potassium Channel K2P1

Alexandria N. Miller et al.

SCIENCE (2012)

Article Biochemistry & Molecular Biology

The hERG K+ channel S4 domain L532P mutation: Characterization at 37 °C

Yi H. Zhang et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2011)

Article Pharmacology & Pharmacy

Carvedilol targets human K2P3.1 (TASK1) K+ leak channels

K. Staudacher et al.

BRITISH JOURNAL OF PHARMACOLOGY (2011)

Article Cell Biology

TASK-1 Channels May Modulate Action Potential Duration of Human Atrial Cardiomyocytes

Sven H. Limberg et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2011)

Article Cell Biology

Knock-Out of the Potassium Channel TASK-1 Leads to a Prolonged QT Interval and a Disturbed QRS Complex

Niels Decher et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Structural models of TREK channels and their gating mechanism

Adina L. Milac et al.

CHANNELS (2011)

Article Cardiac & Cardiovascular Systems

Atrial Fibrillation Pathophysiology Implications for Management

Yu-ki Iwasaki et al.

CIRCULATION (2011)

Article Biochemistry & Molecular Biology

A Specific Two-pore Domain Potassium Channel Blocker Defines the Structure of the TASK-1 Open Pore

Anne K. Streit et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Neurosciences

Alternative splicing determines mRNA translation initiation and function of human K2P10.1 K+ channels

Kathrin Staudacher et al.

JOURNAL OF PHYSIOLOGY-LONDON (2011)

Article Pharmacology & Pharmacy

hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine

Ingo Staudacher et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2011)

Article Pharmacology & Pharmacy

Effect of dronedarone on Na+, Ca2+ and HCN channels

Roman Bogdan et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2011)

Article Medicine, General & Internal

Dronedarone in High-Risk Permanent Atrial Fibrillation

Stuart J. Connolly et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Cardiac & Cardiovascular Systems

Clinical Pharmacology of Dronedarone: Implications for the Therapy of Atrial Fibrillation

Paul Dorian

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS (2010)

Article Medicine, General & Internal

New antiarrhythmic drugs for treatment of atrial fibrillation

Dobromir Dobrev et al.

LANCET (2010)

Article Pharmacology & Pharmacy

The human cardiac K2P3.1 (TASK-1) potassium leak channel is a molecular target for the class III antiarrhythmic drug amiodarone

Jakob Gierten et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2010)

Article Pharmacology & Pharmacy

Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine

Sabrina Obers et al.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2010)

Editorial Material Pharmacology & Pharmacy

Novel pharmacological approaches for antiarrhythmic therapy

Ursula Ravens

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2010)

Review Pharmacology & Pharmacy

Novel Approaches for Pharmacological Management of Atrial Fibrillation

Joachim R. Ehrlich et al.

DRUGS (2009)

Review Biophysics

Two-pore potassium channels in the cardiovascular system

Alison Gurney et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2009)

Article Medicine, General & Internal

Effect of Dronedarone on Cardiovascular Events in Atrial Fibrillation

Stefan H. Hohnloser et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Pharmacology & Pharmacy

Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein

J. Gierten et al.

BRITISH JOURNAL OF PHARMACOLOGY (2008)

Article Cardiac & Cardiovascular Systems

Atrial-selective approaches for the treatment of atrial fibrillation

Joachim R. Ehrlich et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)

Article Biochemistry & Molecular Biology

Does sumoylation control K2P1/TWIK1 background K+ channels?

Sylvain Feliciangeli et al.

Article Cardiac & Cardiovascular Systems

The acid-sensitive potassium channel TASK-1 in rat cardiac muscle

Caroline Putzke et al.

CARDIOVASCULAR RESEARCH (2007)

Article Biochemistry & Molecular Biology

Control of cardiac rhythm by ORK1, a Drosophila two-pore domain potassium channel

Nathalie Lalevee et al.

CURRENT BIOLOGY (2006)

Article Cardiac & Cardiovascular Systems

The stretch-activated potassium channel TREK-1 in rat cardiac ventricular muscle

XT Li et al.

CARDIOVASCULAR RESEARCH (2006)

Article Cardiac & Cardiovascular Systems

Comparing the global mRNA expression profile of human atrial and ventricular myocardium with high-density oligonucleotide arrays

P Ellinghaus et al.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2005)

Article Biochemistry & Molecular Biology

Sumoylation silences the plasma membrane leak K+ channel K2P1

S Rajan et al.

Article Pharmacology & Pharmacy

Heterogeneous expression of tandem-pore K+ channel genes in adult and embryonic rat heart quantified by real-time polymerase chain reaction

W Liu et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2004)

Article Biochemistry & Molecular Biology

High affinity HERG K+ channel blockade by the antiarrhythmic agent dronedarone:: resistance to mutations of the S6 residues Y652 and F656

JM Ridley et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)

Article Cardiac & Cardiovascular Systems

Effects of amiodarone and dronedarone on voltage-dependent sodium current in human cardiomyocytes

N Lalevée et al.

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2003)

Article Cardiac & Cardiovascular Systems

Electrophysiologic characterization of dronedarone in guinea pig ventricular cells

P Gautier et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2003)

Review Multidisciplinary Sciences

Cardiac channelopathies

E Marbán

NATURE (2002)

Review Neurosciences

Properties and modulation of mammalian 2P domain K+ channels

AJ Patel et al.

TRENDS IN NEUROSCIENCES (2001)

Article Cardiac & Cardiovascular Systems

Inhibitory effects of dronedarone on muscarinic K+ current in guinea pig atrial cells

E Guillemare et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2000)

Article Pharmacology & Pharmacy

Effects of dronedarone on Acetylcholine-activated current in rabbit SAN cells

C Altomare et al.

BRITISH JOURNAL OF PHARMACOLOGY (2000)

Article Biochemistry & Molecular Biology

Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3

CMB Lopes et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)