Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 20, Issue 6, Pages 648-650Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb.2602
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Funding
- NIGMS NIH HHS [R01 GM066272] Funding Source: Medline
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Whether centromere-specific CENP-A-containing nucleosomes comprise one molecule each of CENP-A and histones H4, H2A and H2B (forming a tetramer or hemisome) or two molecules of all four histones (forming an octamer) has been controversial. Three new studies now address this controversy using complementary in vitro and in vivo approaches.
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