Related references
Note: Only part of the references are listed.Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Manner in Vitro and in Vivo
Justin Legleiter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Heme proteins-Diversity in structural characteristics, function, and folding
Lorna J. Smith et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2010)
Polyglutamine Induced Misfolding of Huntingtin Exon1 is Modulated by the Flanking Sequences
Vinal V. Lakhani et al.
PLOS COMPUTATIONAL BIOLOGY (2010)
Examining Polyglutamine Peptide Length: A Connection between Collapsed Conformations and Increased Aggregation
Robert H. Walters et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation
Stephen Tam et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism
Ashwani K. Thakur et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice
Xiaofeng Gu et al.
NEURON (2009)
Single homopolypeptide chains collapse into mechanically rigid conformations
Lorna Dougan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The impact of ataxin-1-like histidine insertions on polyglutamine aggregation
Murali Jayaraman et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2009)
Insights into structure, stability, and toxicity of monomeric and aggregated polyglutamine models from molecular dynamics simulations
Luciana Esposito et al.
BIOPHYSICAL JOURNAL (2008)
Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly
Wei-Feng Xue et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
In-cell aggregation of a polyglutamine-containing chimera is a multistep process initiated by the flanking sequence
Zoya Ignatova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Reconsidering the mechanism of polyglutamine peptide aggregation
Christine C. Lee et al.
BIOCHEMISTRY (2007)
Protein aggregation processes: In search of the mechanism
Carl Frieden
PROTEIN SCIENCE (2007)
A toxic monomeric conformer of the polyglutamine protein
Yoshitaka Nagai et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Effects of chain length on the aggregation of model polyglutamine peptides: Molecular dynamics simulations
Alexander J. Marchut et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)
The Interplay between PolyQ and Protein Context Delays Aggregation by Forming a Reservoir of Protofibrils
Donatella Bulone et al.
PLOS ONE (2006)
Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions
Scott L. Crick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Analysis of molecular recognition features (MoRFs)
Amrita Mohan et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins
Natalia Slepko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step
Andrew M. Ellisdon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Characterizing the conformational ensemble of monomeric polyglutamine
XL Wang et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)
Oligoproline effects on polyglutamine conformation and aggregation
A Bhattacharyya et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Nucleation: The connections between equilibrium and kinetic behavior
Frank A. Ferrone
AMYLOID, PRIONS, AND OTHER PROTEIN AGGREGATES, PT B (2006)
Polyglutamine is not all: The functional role of the AXH domain in the ataxin-1 protein
C de Chiara et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Polyglutamine homopolymers having 8-45 residues form slablike β-crystallite assemblies
D Sharma et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2005)
Polyglutamine aggregation nucleation: Thermodynamics of a highly unfavorable protein folding reaction
AM Bhattacharyya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Thermodynamics of Aβ(1-40) amyloid fibril elongation
B O'Nuallain et al.
BIOCHEMISTRY (2005)
Molecular origin of polyglutamine aggregation in neurodegenerative diseases
SD Khare et al.
PLOS COMPUTATIONAL BIOLOGY (2005)
Influence of the N-terminal domain on the aggregation properties of the prion protein
KN Frankenfield et al.
PROTEIN SCIENCE (2005)
New model for crystalline polyglutamine assemblies and their connection with amyloid fibrils
P Sikorski et al.
BIOMACROMOLECULES (2005)
Kinetic analysis of beta-amyloid fibril elongation
MJ Cannon et al.
ANALYTICAL BIOCHEMISTRY (2004)
Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins
P Venkatraman et al.
MOLECULAR CELL (2004)
Mechanism of prion propagation: Amyloid growth occurs by monomer addition
SR Collins et al.
PLOS BIOLOGY (2004)
Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer
JL Wacker et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Mutational analysis of the structural organization of polyglutamine aggregates
AK Thakur et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization
MA Poirier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation
SM Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Amyloid-like features of polyglutamine aggregates and their assembly kinetics
SM Chen et al.
BIOCHEMISTRY (2002)
Identification and characterization of key kinetic intermediates in amyloid β-protein fibrillogenesis
MD Kirkitadze et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity
S Chen et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Solubilization and disaggregation of polyglutamine peptides
SM Chen et al.
PROTEIN SCIENCE (2001)