Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 16, Issue 8, Pages 804-806Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb0809-804
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Bacterial antisense RNAs target translation initiation regions (TIRs) to compete with ribosome binding, thus repressing translation and-secondarily-causing degradation of the naked mRNA. A new study reports on an antisense RNA that directly accelerates mRNA decay by targeting a sequence deep within the coding region, far downstream of the TIR.
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