Journal
NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 15, Issue 2, Pages 123-125Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb0208-123
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Transient mechanical stresses induced by molecular motors that move DNA can propagate through the chromatin fiber and trigger local DNA alterations that in turn allow for specific DNA-protein interactions. Hence, DNA supercoiling modulations and chromatin conformational dynamics concur in gene regulation.
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