4.5 Editorial Material

The type II secretion arrowhead: the structure of GspI-GspJ-GspK

Journal

NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 15, Issue 5, Pages 428-430

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb0508-428

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A heterotrimeric complex of minor pseudopilins from the type II secretion system has been identified and its crystal structure solved. Although each subunit shares the same overall alpha-beta fold as other characterized (pseudo)pilins, GspK has a unique large alpha-helical domain inserted between two canonical beta-strands. The structure constrains models for pseudopilus assembly.

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