Journal
NATURE REVIEWS NEUROSCIENCE
Volume 13, Issue 2, Pages 77-93Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrn3156
Keywords
-
Categories
Funding
- US National Institute of Neurological Disorder and Stroke (NINDS)
- US National Institutes of Health (NIH)
- NIH [K99]
Ask authors/readers for more resources
Mitochondria have a number of essential roles in neuronal function. Their complex mobility patterns within neurons are characterized by frequent changes in direction. Mobile mitochondria can become stationary or pause in regions that have a high metabolic demand and can move again rapidly in response to physiological changes. Defects in mitochondrial transport are implicated in the pathogenesis of several major neurological disorders. Research into the mechanisms that regulate mitochondrial transport is thus an important emerging frontier.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available