Journal
NATURE REVIEWS NEUROSCIENCE
Volume 13, Issue 9, Pages 619-635Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrn3312
Keywords
-
Categories
Funding
- Dutch Organization for Medical Sciences (ZonMw)
- Life Sciences (ALW)
- Senter (NeuroBasic)
- Prinses Beatrix Fonds
- ERC-advanced program of the European Community
- CEREBNET program of the European Community
- C7 program of the European Community
Ask authors/readers for more resources
Studies on synaptic plasticity in the context of learning have been dominated by the view that a single, particular type of plasticity forms the underlying mechanism for a particular type of learning. However, emerging evidence shows that many forms of synaptic and intrinsic plasticity at different sites are induced conjunctively during procedural memory formation in the cerebellum. Here, we review the main forms of long-term plasticity in the cerebellar cortex that underlie motor learning. We propose that the different forms of plasticity in the granular layer and the molecular layer operate synergistically in a temporally and spatially distributed manner, so as to ultimately create optimal output for behaviour.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available