Journal
NATURE REVIEWS NEUROSCIENCE
Volume 11, Issue 8, Pages 577-588Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrn2881
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Funding
- NIGMS NIH HHS [T32 GM007507] Funding Source: Medline
- NINDS NIH HHS [R01 NS063245] Funding Source: Medline
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There has been considerable progress in elucidating the molecular mechanisms that contribute to memory formation and the generation of circadian rhythms. However, it is not well understood how these two processes interact to generate long-term memory. Recent studies in both vertebrate and invertebrate models have shown time-of-day effects on neurophysiology and memory formation, and have revealed a possible role for cycling molecules in memory persistence. Together, these studies suggest that common mechanisms underlie circadian rhythmicity and long-term memory formation.
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