Journal
NATURE REVIEWS NEUROSCIENCE
Volume 10, Issue 8, Pages 549-560Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrn2683
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Funding
- US National Institutes of Health [P20 MH077967, R01 GM075315]
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It has been known for a long time that genetic factors affect sleep quantity and quality. Genetic screens have identified several mutations that affect sleep across species, pointing to an evolutionary conserved regulation of sleep. Moreover, it has also been recognized that sleep affects gene expression. These findings have given valuable insights into the molecular underpinnings of sleep regulation and function that might lead the way to more efficient treatments for sleep disorders.
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