Journal
NATURE REVIEWS NEUROSCIENCE
Volume 10, Issue 9, Pages 627-634Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrn2681
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Funding
- National Institutes of Health (NIH), USA [MH70000]
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Although WNTs have been long thought of as regulators of cell fate, recent studies highlight their involvement in crucial aspects of synaptic development in the nervous system. Particularly compelling are recent studies of the neuromuscular junction in nematodes, insects, fish and mammals. These studies place WNTs as major determinants of synapse differentiation and neurotransmitter receptor clustering.
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