Related references
Note: Only part of the references are listed.α-Synuclein oligomers and clinical implications for Parkinson disease
Lorraine V. Kalia et al.
ANNALS OF NEUROLOGY (2013)
Lipid Peroxidation Product 4-Hydroxy-2-Nonenal Promotes Seeding-Capable Oligomer Formation and Cell-to-Cell Transfer of α-Synuclein
Eun-Jin Bae et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Prion-like spreading of pathological α-synuclein in brain
Masami Masuda-Suzukake et al.
BRAIN (2013)
Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
Jing L. Guo et al.
CELL (2013)
Unconventional protein secretion: an evolving mechanism
Vivek Malhotra
EMBO JOURNAL (2013)
Tubulin Polymerization-promoting Protein (TPPP/p25α) Promotes Unconventional Secretion of α-Synuclein through Exophagy by Impairing Autophagosome-Lysosome Fusion
Patrick Ejlerskov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Parkinson's Disease and Alpha Synuclein: Is Parkinson's Disease a Prion-Like Disorder?
C. Warren Olanow et al.
MOVEMENT DISORDERS (2013)
The many faces of alpha-synuclein: from structure and toxicity to therapeutic target
Hilal A. Lashuel et al.
NATURE REVIEWS NEUROSCIENCE (2013)
The pathology roadmap in Parkinson disease
D. James Surmeier et al.
PRION (2013)
Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia
Changyoun Kim et al.
NATURE COMMUNICATIONS (2013)
Autophagic failure promotes the exocytosis and intercellular transfer of α-synuclein
He-Jin Lee et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2013)
Targeting intracellular and extracellular alpha-synuclein as a therapeutic strategy in Parkinson's disease and other synucleinopathies
Kostas Vekrellis et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2012)
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
Kelvin C. Luk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
α-Synuclein in human cerebrospinal fluid is principally derived from neurons of the central nervous system
Brit Mollenhauer et al.
JOURNAL OF NEURAL TRANSMISSION (2012)
Extracellular Alpha-Synuclein Oligomers Modulate Synaptic Transmission and Impair LTP Via NMDA-Receptor Activation
Maria Jose Diogenes et al.
JOURNAL OF NEUROSCIENCE (2012)
Antibody-Aided Clearance of Extracellular α-Synuclein Prevents Cell-to-Cell Aggregate Transmission
Eun-Jin Bae et al.
JOURNAL OF NEUROSCIENCE (2012)
Exosomal cell-to-cell transmission of alpha synuclein oligomers
Karin M. Danzer et al.
MOLECULAR NEURODEGENERATION (2012)
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
Kelvin C. Luk et al.
SCIENCE (2012)
Alpha-synuclein: from secretion to dysfunction and death
O. Marques et al.
CELL DEATH & DISEASE (2012)
Toll-Like Receptor 4 Promotes α-Synuclein Clearance and Survival of Nigral Dopaminergic Neurons
Nadia Stefanova et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Dopamine promotes formation and secretion of non-fibrillar alpha-synuclein oligomers
He-Jin Lee et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2011)
Heat-shock protein 70 modulates toxic extracellular alpha-synuclein oligomers and rescues trans-synaptic toxicity
Karin M. Danzer et al.
FASEB JOURNAL (2011)
α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
Christian Hansen et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study (vol 10, pg 230, 2011)
B. Mollenhauer et al.
LANCET NEUROLOGY (2011)
Glia: Initiators and Progressors of Pathology in Parkinson's Disease
Glenda M. Halliday et al.
MOVEMENT DISORDERS (2011)
Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
Laura A. Volpicelli-Daley et al.
NEURON (2011)
Protein aggregate spreading in neurodegenerative diseases: Problems and perspectives
Seung-Jae Lee et al.
NEUROSCIENCE RESEARCH (2011)
Assessment of α-Synuclein Secretion in Mouse and Human Brain Parenchyma
Evangelia Emmanouilidou et al.
PLOS ONE (2011)
The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of α-Synuclein
Takafumi Hasegawa et al.
PLOS ONE (2011)
α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study
Brit Mollenhauer et al.
LANCET NEUROLOGY (2011)
Microglia: biology and pathology
Manuel B. Graeber et al.
ACTA NEUROPATHOLOGICA (2010)
Quantification of alpha-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies
Brit Mollenhauer et al.
BIOMARKERS IN MEDICINE (2010)
DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease
Zhen Hong et al.
BRAIN (2010)
Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
He-Jin Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation
Ravi Manjithaya et al.
JOURNAL OF CELL BIOLOGY (2010)
Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival
Evangelia Emmanouilidou et al.
JOURNAL OF NEUROSCIENCE (2010)
Prion-like transmission of protein aggregates in neurodegenerative diseases
Patrik Brundin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Cell-to-cell transmission of non-prion protein aggregates
Seung-Jae Lee et al.
NATURE REVIEWS NEUROLOGY (2010)
Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease
T. Tokuda et al.
NEUROLOGY (2010)
Alpha-synuclein stimulation of astrocytes Potential role for neuroinflammation and neuroprotection
He-Jin Lee et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2010)
Neuroinflammation in Parkinson's disease: a target for neuroprotection?
Etienne C. Hirsch et al.
LANCET NEUROLOGY (2009)
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein
Paula Desplats et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A critical reappraisal of current staging of Lewy-related pathology in human brain
Kurt A. Jellinger
ACTA NEUROPATHOLOGICA (2008)
Clearance and deposition of extracellular α-synuclein aggregates in microglia
He-Jin Lee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein
He-Jin Lee et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2008)
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
Jia-Yi Li et al.
NATURE MEDICINE (2008)
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
Jeffrey H. Kordower et al.
NATURE MEDICINE (2008)
Red blood cells are the major source of alpha-synuclein in blood
Robin Barbour et al.
NEURODEGENERATIVE DISEASES (2008)
Invited Article: Nervous system pathology in sporadic Parkinson disease
Heiko Braak et al.
NEUROLOGY (2008)
Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease
Ashley D. Reynolds et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Origins and effects of extracellular alpha-synuclein: Implications in Parkinson's disease
Seung-Jae Lee
JOURNAL OF MOLECULAR NEUROSCIENCE (2008)
Toll-like receptors modulate adult hippocampal neurogenesis
Asya Rolls et al.
NATURE CELL BIOLOGY (2007)
Different species of α-synuclein oligomers induce calcium influx and seeding
Karin M. Danzer et al.
JOURNAL OF NEUROSCIENCE (2007)
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits
Sung-Chun Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The Parkinson's complex: Parkinsonism is just the tip of the iceberg
JW Langston
ANNALS OF NEUROLOGY (2006)
Burden of illness in Parkinson's disease
DM Huse et al.
MOVEMENT DISORDERS (2005)
Proteolytic cleavage of extracellular secreted α-synuclein via matrix metalloproteinases
JY Sung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Intravesicular localization and exocytosis of α-synuclein and its aggregates
HJ Lee et al.
JOURNAL OF NEUROSCIENCE (2005)
Aggregated α-synuclein activates microglia:: a process leading to disease progression in Parkinson's disease
W Zhang et al.
FASEB JOURNAL (2005)
Clearance of α-synuclein oligomeric intermediates via the lysosomal degradation pathway
HJ Lee et al.
JOURNAL OF NEUROSCIENCE (2004)
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
AM Cuervo et al.
SCIENCE (2004)
α-synuclein is degraded by both autophagy and the proteasome
JL Webb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)