Journal
NATURE REVIEWS NEPHROLOGY
Volume 5, Issue 8, Pages 436-437Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrneph.2009.109
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ONTARGET showed that dual renin-angiotensin system blockade prevents microalbuminuria but facilitates transient renal function impairment in nonproteinuric patients with atherosclerotic vascular disease or diabetes. These findings should not be used as an excuse not to optimize renin angiotensin system inhibition and target urinary protein in patients with proteinuric nephropathies.
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