Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 15, Issue 12, Pages 825-833Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm3903
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Funding
- American Heart Association
- Marie Curie International Outgoing Fellowship within the Seventh European Commission Framework Programme [PIOF-GA-2012-332045]
- Mechanobiology Institute, National University of Singapore
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Although the shapes of organisms are encoded in their genome, the developmental processes that lead to the final form of vertebrates involve a constant feedback between dynamic mechanical forces, and cell growth and motility. Mechanobiology has emerged as a discipline dedicated to the study of the effects of mechanical forces and geometry on cell growth and motility - for example, during cell matrix adhesion development - through the signalling process of mechanotransduction.
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