4.7 Review

AMPK: a nutrient and energy sensor that maintains energy homeostasis

Related references

Note: Only part of the references are listed.
Editorial Material Biochemistry & Molecular Biology

Cysteine 38 Holds the Key to NF-κB Activation

Neil D. Perkins

MOLECULAR CELL (2012)

Review Biochemistry & Molecular Biology

The ATM protein kinase and cellular redox signaling: beyond the DNA damage response

Scott Ditch et al.

TRENDS IN BIOCHEMICAL SCIENCES (2012)

Review Endocrinology & Metabolism

AMPK functions as an adenylate charge-regulated protein kinase

Jonathan S. Oakhill et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)

Article Biochemistry & Molecular Biology

Metformin Activates AMP Kinase through Inhibition of AMP Deaminase

Jiangyong Ouyang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Subunit and Domain Requirements for Adenylate-mediated Protection of Snf1 Kinase Activation Loop from Dephosphorylation

Dakshayini G. Chandrashekarappa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Multidisciplinary Sciences

Structure of mammalian AMPK and its regulation by ADP

Bing Xiao et al.

NATURE (2011)

Article Cell Biology

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim et al.

NATURE CELL BIOLOGY (2011)

Review Biochemistry & Molecular Biology

Central mechanisms involved in the orexigenic actions of ghrelin

Zane B. Andrews

PEPTIDES (2011)

Article Multidisciplinary Sciences

Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability

Naoko Ikematsu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

AMP-activated protein kinase (AMPK) β1β2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

Hayley M. O'Neill et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

AMPK Is a Direct Adenylate Charge-Regulated Protein Kinase

Jonathan S. Oakhill et al.

SCIENCE (2011)

Review Biochemistry & Molecular Biology

AMP-activated protein kinase: also regulated by ADP?

D. Grahame Hardie et al.

TRENDS IN BIOCHEMICAL SCIENCES (2011)

Article Oncology

IONIZING RADIATION ACTIVATES AMP-ACTIVATED KINASE (AMPK): A TARGET FOR RADIOSENSITIZATION OF HUMAN CANCER CELLS

Toran Sanli et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2010)

Article Agriculture, Multidisciplinary

Hispidulin Potently Inhibits Human Glioblastoma Multiforme Cells through Activation of AMP-Activated Protein Kinase (AMPK)

Ying-Chao Lin et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Exposure to Hydrogen Peroxide Induces Oxidation and Activation of AMP-activated Protein Kinase

Jaroslaw W. Zmijewski et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Medicine, Research & Experimental

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

Marc Foretz et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Multidisciplinary Sciences

Network organization of the human autophagy system

Christian Behrends et al.

NATURE (2010)

Article Biochemistry & Molecular Biology

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

Miguel Lopez et al.

NATURE MEDICINE (2010)

Article Multidisciplinary Sciences

β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK)

Jonathan S. Oakhill et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

Angela Alexander et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Endocrinology & Metabolism

Interactions of the circadian CLOCK system and the HPA axis

Nancy Nader et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)

Article Biochemical Research Methods

Action Potential Energy Efficiency Varies Among Neuron Types in Vertebrates and Invertebrates

Biswa Sengupta et al.

PLOS COMPUTATIONAL BIOLOGY (2010)

Article Endocrinology & Metabolism

Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle

Christian Pehmoller et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)

Article Biochemistry & Molecular Biology

Uncoupling of oxidative phosphorylation by curcumin: Implication of its cellular mechanism of action

Han Wern Lim et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

Article Biochemistry & Molecular Biology

Crucial role for LKB1 to AMPK alpha 2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes

Daphna D. J. Habets et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2009)

Article Endocrinology & Metabolism

Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle

J. T. Treebak et al.

DIABETOLOGIA (2009)

Article Multidisciplinary Sciences

AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply

Sven Hoppe et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Multidisciplinary Sciences

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation

Katja A. Lamia et al.

SCIENCE (2009)

Review Endocrinology & Metabolism

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

Kei Sakamoto et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)

Article Biochemistry & Molecular Biology

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators

Shuai Chen et al.

BIOCHEMICAL JOURNAL (2008)

Article Biochemistry & Molecular Biology

AMPK and PPARδ Agonists are exercise mimetics

Vihang A. Narkar et al.

Article Cell Biology

Hypothalamic CaMKK2 contributes to the regulation of energy balance

Kristin A. Anderson et al.

CELL METABOLISM (2008)

Article Biochemistry & Molecular Biology

AMPK phosphorylation of raptor mediates a metabolic checkpoint

Dana M. Gwinn et al.

MOLECULAR CELL (2008)

Article Multidisciplinary Sciences

Etoposide Induces ATM-Dependent Mitochondrial Biogenesis through AMPK Activation

Xuan Fu et al.

PLOS ONE (2008)

Article Biochemistry & Molecular Biology

Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR

Kathryn M. Geraghty et al.

BIOCHEMICAL JOURNAL (2007)

Article Biochemistry & Molecular Biology

The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor

Eric L. Greer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C-elegans

Eric L. Greer et al.

CURRENT BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Structural insight into AMPK regulation: ADP comes into play

Xiangshu Jin et al.

STRUCTURE (2007)

Review Cell Biology

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

D. Grahame Hardie

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)

Article Multidisciplinary Sciences

Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1

Gabriele A. Amodeo et al.

NATURE (2007)

Article Multidisciplinary Sciences

Structural basis for AMP binding to mammalian AMP-activated protein kinase

Bing Xiao et al.

NATURE (2007)

Article Medicine, Research & Experimental

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

Marc Claret et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Multidisciplinary Sciences

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Sibylle Jaeger et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Energy-dependent regulation of cell structure by AMP-activated protein kinase

Jun Hee Lee et al.

NATURE (2007)

Article Multidisciplinary Sciences

Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase

Robert Townley et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

Conserved α-helix acts as autoinhibitory sequence in AMP-activated protein kinase α subunits

Tao Pang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Multidisciplinary Sciences

Resveratrol improves health and survival of mice on a high-calorie diet

Joseph A. Baur et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Dissecting the role of 5′-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase

Marianne Suter et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Endocrinology & Metabolism

Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKα2 but not AMPKα1

K Sakamoto et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)

Article Biochemistry & Molecular Biology

Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase

JT Hwang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)

Review Cell Biology

CBS domains: structure, function, and pathology in human proteins

S Ignoul et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)

Article Multidisciplinary Sciences

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

SH Koo et al.

NATURE (2005)

Article Biochemistry & Molecular Biology

The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases

RL Hurley et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase

B Kola et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

K Sakamoto et al.

EMBO JOURNAL (2005)

Article Biochemistry & Molecular Biology

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

RG Jones et al.

MOLECULAR CELL (2005)

Article Biochemistry & Molecular Biology

AMP-activated protein kinase plays a role in the control of food intake

U Andersson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

RJ Shaw et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

TSC2 mediates cellular energy response to control cell growth and survival

K Inoki et al.

Article Biochemistry & Molecular Biology

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

A Woods et al.

CURRENT BIOLOGY (2003)

Article Biochemistry & Molecular Biology

AMPK β subunit targets metabolic stress sensing to glycogen

G Polekhina et al.

CURRENT BIOLOGY (2003)

Article Biochemistry & Molecular Biology

The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways

LGD Fryer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Medicine, Research & Experimental

Role of AMP-activated protein kinase in mechanism of metformin action

GC Zhou et al.

JOURNAL OF CLINICAL INVESTIGATION (2001)

Review Endocrinology & Metabolism

An energy budget for signaling in the grey matter of the brain

D Attwell et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2001)

Article Agriculture, Multidisciplinary

Method for the quantitative extraction of resveratrol and piceid isomers in grape berry skins. Effect of powdery mildew on the stilbene content

AI Romero-Perez et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2001)