Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 11, Issue 1, Pages 75-81Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm2818
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Funding
- National Institutes of Health [AR44232]
- NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES [R01AR044232] Funding Source: NIH RePORTER
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The cytoskeleton is an intricate and dynamic fibrous network that has an essential role in the generation and regulation of cell architecture and cellular mechanical properties. The cytoskeleton also evolved as a scaffold that supports diverse biochemical pathways. Recent evidence favours the hypothesis that the cytoskeleton participates in the spatial organization and regulation of translation, at both the global and local level, in a manner that is crucial for cellular growth, proliferation and function.
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